PBN contains one specific oral proteolytic enzyme that deserves special mention since it is the only enzyme listed in the PDR as an orally administered anti-inflammatory enzyme approved for use in the U.S. Outside the U.S., proteolytic enzymes are used more extensively as ethical, approved medical treatments. They are frequently used for the treatment of arthritides, multiple sclerosis, autoimmune disorders, and cancer. In Korea and Europe, cancer mortality is decreased (23%) with reductions in relapses. Impress yourself, with all the anti-inflammatory benefits you can provide yourself with 2-3 tablespoons taken daily of PBN. (PDR approved).